Main Quest Guide
Main story route, major mission choices and the requirements for Cyberpunk 2077's base-game ending paths. Contains spoilers.
Prologue: Life paths
Choose Nomad, Streetkid or Corpo. Each has a unique opening mission, but all three converge when V teams up with Jackie Welles.
Your life path unlocks unique dialogue options across the whole game, so pick the one whose flavor you enjoy most.
Act 1: The Heist
Act 1 builds to 'The Heist' at Konpeki Plaza in Watson. Watson side jobs remain available later; explore now if you want money and equipment before the heist.
Key missions: 'The Ripperdoc', 'The Information', 'The Pickup' and 'The Heist'. Your choices in 'The Pickup' change how Maelstrom treats you.
Act 2: Three paths
After 'Playing for Time', follow three leads: Evelyn through Judy and then the Voodoo Boys; Hellman through Rogue and Panam; and Arasaka through Takemura. These lead through 'Automatic Love', 'Ghost Town' and 'Down on the Street'.
Panam's side jobs unlock the Aldecaldos ending option. Johnny and Rogue's side jobs unlock Rogue's assault. Judy, River and Kerry affect relationships and epilogues, but do not independently unlock assault routes.
Preparing your allies
For the Aldecaldos route, complete Panam's 'Riders on the Storm', 'With a Little Help from My Friends' and 'Queen of the Highway'. Do not betray her plan to Saul.
For Rogue's route, follow Johnny's 'Chippin' In' and finish 'Blistering Love'. The secret assault requires specific dialogue in the oilfield conversation in 'Chippin' In'; a high Johnny relationship percentage alone is not enough.
Endings
Meeting Hanako at Embers starts the finale; choose your approach later on Misty's rooftop. Hanako's option is available without the ally side-job chains. Save Takemura during 'Search and Destroy' if you want him present in that route.
Save before 'Nocturne Op55N1' — it's the point of no return.